01Start here
Product introduction
Flupentixol is a dopamine-receptor antagonist and melitracen is a tricyclic antidepressant. The combination has been used in some markets for selected anxiety/depressive symptom presentations, but approved indications vary by country.
Mood symptoms, panic, sleep disruption and physical symptoms can have different causes. Treatment requires diagnosis, a follow-up plan and active monitoring for adverse effects or worsening mental health.
Important contextThis page explains the composition and general ingredient context. The approved local product label remains the authority for indication, dose, contraindications and monitoring.
02Clinical context
Uses of KRIXOL-M
- ✓Only for the locally approved indication selected by a qualified prescriber.
- ✓Part of a broader care plan that may include psychological treatment, sleep and substance-use review, and follow-up.
- ✓Not appropriate for self-diagnosed stress, occasional sadness or unsupervised long-term use.
Benefits and product context
01Clinician-selected combination
Combines medicines acting on different neurotransmitter systems in one tablet.
02Structured follow-up
Treatment response, activation, movement effects, mood and physical adverse effects can be reviewed together.
03Defined care plan
Best used with clear goals, duration and a discontinuation strategy determined by the prescriber.
03Know what to watch for
Side effects and warning signs
Possible effects include dry mouth, constipation, blurred vision, dizziness, sleep change, restlessness, sweating or a faster heartbeat.
!Suicidal thoughts, severe agitation or sudden behavioural change
!High fever, severe stiffness, confusion or reduced consciousness
!New tremor, rigidity, involuntary movement or marked restlessness
!Fainting, seizure, severe allergy or an irregular heartbeat
When to seek helpSeek urgent help for suicidal thoughts, severe behavioural change, high fever with rigidity, fainting, seizure or a severe allergic reaction.
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AdministrationHow to use KRIXOL-M
Take exactly as prescribed and at the advised time of day. Do not share it, increase the dose, stop suddenly or combine it with alcohol or sedating substances without advice. Attend early follow-up, especially after starting or changing the dose.
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MechanismHow it works
Flupentixol blocks dopamine receptors; melitracen inhibits reuptake of serotonin and noradrenaline. These actions also explain important neurological, anticholinergic, cardiovascular and mood-related precautions. The combination’s local approved indication and product literature are authoritative.
04Use with care
Safety advice
01
Pregnancy
Specialist decisionPregnancy or planning pregnancy requires prompt specialist review of risks, benefits and alternatives.
02
Breastfeeding
Specialist decisionA clinician should assess whether this product is appropriate while breastfeeding.
03
Driving
May impair drivingDrowsiness, dizziness, blurred vision or impaired reactions can occur. Do not drive until the prescriber confirms it is safe and you know your response.
04
Kidney health
Medical reviewMedical history and current function should be reviewed as part of safe prescribing.
05
Liver health
Dose/medicine reviewLiver impairment can alter medicine handling and requires prescriber assessment.
Practical checklistQuick tips
Small steps that support safer, more informed use.
- ✓Arrange follow-up soon after starting or changing therapy.
- ✓Tell a trusted person how to seek help if mood suddenly worsens.
- ✓Avoid alcohol and unreviewed sedatives.
- ✓Rise slowly if dizzy and do not drive if impaired.
- ✓Do not stop abruptly without a prescriber-led plan.
05At a glance
Product fact box
Product categoryPrescription neuropsychiatric medicine
Therapy areaNeuro & Wellness
Dosage formTablet
Habit formingNo known habit-forming potential
CompanyWipzo Healthcare Private Limited
Information statusProfessional reference
06Medicine review
Interactions and combinations
Give your prescriber or pharmacist a complete list of prescription medicines, over-the-counter products, vitamins, herbals and supplements.
ReviewMAO inhibitors and other antidepressants
Potentially serious interactions require prescriber-led timing and monitoring.
ReviewAlcohol, sedatives and opioids
These can worsen drowsiness, impaired coordination and breathing risk.
ReviewQT-prolonging or rhythm-affecting medicines
The combination requires review alongside heart-rhythm medicines and electrolyte disturbances.
ReviewAnticholinergic medicines
Dry mouth, constipation, urinary retention, blurred vision and confusion can worsen.
07Common questions
Frequently asked questions
Is KRIXOL-M a sleeping tablet?+
No. It is a prescription neuropsychiatric combination with important mood, neurological and cardiovascular precautions.
Can I stop when I feel better?+
Do not stop abruptly. Ask the prescriber for a reviewed continuation or taper plan.
Can I drink alcohol?+
Alcohol can worsen sedation, judgement and other adverse effects and should be discussed with the prescriber.
What if my mood worsens?+
Contact the treating clinician urgently. Seek immediate emergency help for suicidal thoughts or inability to stay safe.
Ingredient-information references
General ingredient context was reviewed against authoritative health or regulatory resources. These links are not a substitute for the approved Wipzo product label.
