/* Premium product-information system */
.pi-page{
  --pi-navy:#082b68;
  --pi-blue:#1679e8;
  --pi-cyan:#21a9ef;
  --pi-ink:#102f61;
  --pi-copy:#5b7395;
  --pi-line:#dce8f5;
  --pi-soft:#f4f9ff;
  background:#f6faff;
  color:var(--pi-ink);
}
.pi-page *{box-sizing:border-box}
.pi-hero{position:relative;overflow:hidden;background:radial-gradient(circle at 82% 28%,rgba(62,178,249,.2),transparent 28%),linear-gradient(132deg,#fbfdff 0%,#f1f8ff 48%,#e8f5ff 100%);border-bottom:1px solid var(--pi-line)}
.pi-hero-grid-pattern{position:absolute;inset:0;background-image:radial-gradient(rgba(20,113,206,.1) 1px,transparent 1px);background-size:25px 25px;mask-image:linear-gradient(90deg,#000 0%,transparent 64%);opacity:.45}
.pi-breadcrumb{position:relative;z-index:2;display:flex;align-items:center;gap:9px;flex-wrap:wrap;padding-top:26px;color:#7187a6;font-size:11px;font-weight:750}
.pi-breadcrumb a{color:#567498}.pi-breadcrumb a:hover{color:var(--pi-blue)}.pi-breadcrumb span{color:#a9b9cd}.pi-breadcrumb strong{color:#234974}
.pi-hero-layout{position:relative;z-index:1;display:grid;grid-template-columns:1.02fr .98fr;gap:72px;align-items:center;min-height:640px;padding:42px 0 74px}
.pi-hero-copy{max-width:690px}.pi-hero-labels{display:flex;align-items:center;gap:10px;flex-wrap:wrap;margin-bottom:18px}
.pi-therapy-pill,.pi-information-pill{display:inline-flex;align-items:center;border-radius:999px;text-transform:uppercase;letter-spacing:.115em;font-size:9px;font-weight:900}
.pi-therapy-pill{padding:8px 13px;background:#e4f2ff;color:#0871d6;border:1px solid #cce6ff}.pi-information-pill{padding:8px 12px;background:rgba(255,255,255,.8);color:#5b7598;border:1px solid #dce8f4}.pi-information-pill i{width:7px;height:7px;border-radius:50%;background:#23bf83;margin-right:7px;box-shadow:0 0 0 4px rgba(35,191,131,.12)}
.pi-hero h1{font-size:clamp(58px,6vw,88px);line-height:.93;letter-spacing:-.06em;color:#0a2f68;margin:0}.pi-product-label{margin:13px 0 23px;color:#1976d2;text-transform:uppercase;letter-spacing:.14em;font-size:11px;font-weight:900}
.pi-composition-card{display:flex;flex-direction:column;gap:8px;padding:20px 22px;border-radius:20px;background:rgba(255,255,255,.86);border:1px solid rgba(195,219,243,.9);box-shadow:0 14px 36px rgba(16,75,139,.08);backdrop-filter:blur(12px)}
.pi-composition-card>span{font-size:9px;letter-spacing:.13em;text-transform:uppercase;color:#6d89a9;font-weight:900}.pi-composition-card strong{font-size:17px;line-height:1.5;color:#163e70}.pi-composition-card small{font-size:10px;color:#7890ae}
.pi-summary{font-size:16px;line-height:1.75;color:var(--pi-copy);margin:21px 0 0;max-width:650px}.pi-hero-actions{display:flex;gap:11px;flex-wrap:wrap;margin-top:27px}
.pi-primary-action,.pi-secondary-action{display:inline-flex;align-items:center;justify-content:center;gap:14px;min-height:50px;padding:0 20px;border-radius:14px;font-size:12px;font-weight:850;transition:.28s ease}.pi-primary-action{color:#fff;background:linear-gradient(135deg,#0d57c4,#1588ea);box-shadow:0 13px 28px rgba(13,104,210,.24)}.pi-secondary-action{color:#174c86;background:#fff;border:1px solid #d5e5f4}.pi-primary-action:hover,.pi-secondary-action:hover{transform:translateY(-3px);box-shadow:0 17px 32px rgba(13,75,145,.16)}
.pi-hero-visual{position:relative;min-height:500px;display:grid;place-items:center;perspective:1000px}.pi-visual-orbit{position:absolute;width:510px;height:510px;border-radius:50%;right:-20px;top:-8px;border:1px solid rgba(30,135,225,.14);box-shadow:0 0 0 56px rgba(44,159,237,.035),0 0 0 112px rgba(44,159,237,.025)}.pi-visual-orbit:before{content:"";position:absolute;inset:70px;border:1px dashed rgba(29,135,227,.2);border-radius:50%}
.pi-product-frame{position:relative;width:min(100%,620px);padding:11px;border-radius:30px;background:rgba(255,255,255,.94);border:1px solid rgba(255,255,255,.98);box-shadow:0 30px 75px rgba(10,69,135,.18);transform:rotateY(-2deg);overflow:hidden}.pi-product-frame>img{display:block;width:100%;aspect-ratio:4/3;object-fit:contain;border-radius:21px;background:#f8fbff}.pi-frame-top,.pi-frame-bottom{display:flex;align-items:center;justify-content:space-between;gap:14px;padding:9px 12px;color:#234e81}.pi-frame-top span{font-size:9px;letter-spacing:.12em;text-transform:uppercase;font-weight:850}.pi-frame-top i{display:inline-block;width:7px;height:7px;border-radius:50%;background:#1fc789;margin-right:6px}.pi-frame-top b{font-size:10px;text-transform:uppercase;letter-spacing:.08em}.pi-frame-bottom{padding:12px 12px 8px}.pi-frame-bottom span{font-size:9px;text-transform:uppercase;letter-spacing:.11em;color:#7b92ae}.pi-frame-bottom strong{font-size:16px;color:#0c3975}
.pi-rx-note{position:absolute;left:-20px;bottom:23px;display:flex;align-items:center;gap:12px;max-width:265px;padding:13px 15px;border-radius:17px;background:#092f69;color:#fff;box-shadow:0 19px 38px rgba(6,44,96,.25)}.pi-rx-note>span{width:36px;height:36px;display:grid;place-items:center;border-radius:11px;background:linear-gradient(135deg,#269cf1,#0f65c7);font-size:13px;font-weight:900}.pi-rx-note b,.pi-rx-note small{display:block}.pi-rx-note b{font-size:12px}.pi-rx-note small{font-size:9px;color:#bed7ee;line-height:1.35;margin-top:3px}
.pi-contact-strip{background:#fff;border-bottom:1px solid var(--pi-line);box-shadow:0 10px 26px rgba(21,65,114,.035)}.pi-contact-strip .container{display:grid;grid-template-columns:44px 1fr auto;gap:14px;align-items:center;padding-top:18px;padding-bottom:18px}.pi-contact-icon{width:42px;height:42px;display:grid;place-items:center;border-radius:13px;background:#e7f4ff;color:#0876dc;font-weight:900}.pi-contact-strip strong,.pi-contact-strip span{display:block}.pi-contact-strip strong{font-size:13px;color:#163b70}.pi-contact-strip div>span{font-size:11px;color:#7186a3;margin-top:3px}.pi-contact-strip>a{display:flex;align-items:center;gap:12px;padding:12px 16px;border-radius:12px;background:#edf6ff;color:#0b66c5;font-size:11px;font-weight:900}.pi-contact-strip>a span{margin:0;color:inherit}
.pi-section-nav{position:sticky;top:82px;z-index:32;background:rgba(255,255,255,.92);backdrop-filter:blur(18px);border-bottom:1px solid var(--pi-line)}.pi-section-nav .container{display:flex;align-items:center;gap:4px;overflow:auto;scrollbar-width:none}.pi-section-nav .container::-webkit-scrollbar{display:none}.pi-section-nav a{flex:0 0 auto;padding:16px 14px;border-bottom:2px solid transparent;color:#617b9d;font-size:10px;font-weight:850;text-transform:uppercase;letter-spacing:.075em}.pi-section-nav a:hover{color:#086dce;border-color:#1685eb}
.pi-content{padding:68px 0 86px}.pi-content-layout{display:grid;grid-template-columns:minmax(0,1fr) 330px;gap:30px;align-items:start}.pi-main-column{display:grid;gap:22px;min-width:0}
.pi-section-card{scroll-margin-top:155px;padding:40px 42px;border-radius:27px;background:#fff;border:1px solid var(--pi-line);box-shadow:0 14px 36px rgba(13,63,118,.065)}.pi-section-card>p{font-size:15px;line-height:1.82;color:var(--pi-copy);margin:0}.pi-section-card>p+p{margin-top:15px}
.pi-section-heading{display:flex;align-items:flex-start;gap:16px;margin-bottom:26px}.pi-section-heading>span{width:42px;height:42px;flex:none;display:grid;place-items:center;border-radius:14px;background:linear-gradient(145deg,#eaf6ff,#fff);border:1px solid #d7eafc;color:#0b7cdf;font-size:10px;font-weight:900;box-shadow:0 8px 18px rgba(23,111,194,.08)}.pi-section-heading small,.pi-sidebar-kicker{display:block;text-transform:uppercase;letter-spacing:.13em;font-size:8px;font-weight:900;color:#1684e0;margin-bottom:5px}.pi-section-heading h2{font-size:clamp(28px,3vw,40px);line-height:1.05;letter-spacing:-.045em;color:#0c326b;margin:0}.pi-section-heading.compact{margin-bottom:21px}
.pi-context-note{display:grid;grid-template-columns:130px 1fr;gap:18px;padding:16px 18px;border-radius:15px;background:#f1f7fe;border-left:3px solid #1886e7;margin-top:23px}.pi-context-note b{font-size:10px;text-transform:uppercase;letter-spacing:.08em;color:#0c5fb6}.pi-context-note span{font-size:11px;line-height:1.6;color:#637d9d}
.pi-check-list{display:grid;gap:10px;margin:0;padding:0;list-style:none}.pi-check-list li{display:grid;grid-template-columns:30px 1fr;gap:12px;align-items:start;padding:14px 16px;border-radius:15px;background:#f7fbff;border:1px solid #e1ebf5}.pi-check-list i{width:28px;height:28px;display:grid;place-items:center;border-radius:10px;background:#def5eb;color:#129863;font-size:11px;font-style:normal;font-weight:900}.pi-check-list span{font-size:13px;line-height:1.6;color:#486888;padding-top:4px}
.pi-subheading{font-size:22px;letter-spacing:-.03em;color:#12386e;margin:30px 0 16px}.pi-benefit-grid{display:grid;grid-template-columns:repeat(3,1fr);gap:12px}.pi-benefit-grid>div{position:relative;padding:20px;border-radius:18px;background:linear-gradient(145deg,#f8fbff,#edf6ff);border:1px solid #dce9f6;overflow:hidden}.pi-benefit-grid>div>span{position:absolute;right:12px;top:8px;font-size:35px;font-weight:900;color:rgba(20,117,206,.08)}.pi-benefit-grid h4{font-size:13px;color:#123a70;margin:0 0 8px}.pi-benefit-grid p{font-size:11px;line-height:1.58;color:#6b819d;margin:0}
.pi-side-effects{background:linear-gradient(145deg,#fff,#fbfdff)}.pi-alert-list{display:grid;grid-template-columns:1fr 1fr;gap:9px;margin-top:20px}.pi-alert-list>div{display:flex;align-items:center;gap:10px;padding:12px 14px;border:1px solid #f1dddd;background:#fffafa;border-radius:13px}.pi-alert-list i{width:25px;height:25px;flex:none;display:grid;place-items:center;border-radius:8px;background:#ffe5e5;color:#c94f4f;font-style:normal;font-size:10px;font-weight:900}.pi-alert-list span{font-size:11px;line-height:1.45;color:#765b65}.pi-urgent-note{display:grid;grid-template-columns:135px 1fr;gap:18px;margin-top:17px;padding:15px 17px;border-radius:14px;background:#fff2e6;border:1px solid #f7ddc5}.pi-urgent-note b{font-size:10px;text-transform:uppercase;letter-spacing:.08em;color:#ad5d1b}.pi-urgent-note span{font-size:11px;line-height:1.55;color:#826147}
.pi-two-column{display:grid;grid-template-columns:1fr 1fr;gap:22px;scroll-margin-top:155px}.pi-two-column .pi-section-card{min-height:100%}.pi-two-column .pi-section-card>small{font-size:8px;text-transform:uppercase;letter-spacing:.13em;color:#1684e0;font-weight:900}.pi-two-column h2{font-size:29px;line-height:1.05;letter-spacing:-.04em;color:#0d346d;margin:11px 0 17px}.pi-mini-icon{width:44px;height:44px;display:grid;place-items:center;margin-bottom:22px;border-radius:14px;background:linear-gradient(145deg,#0e61c8,#1594ec);color:#fff;font-size:17px;box-shadow:0 12px 25px rgba(15,112,213,.21)}
.pi-safety-list{border:1px solid var(--pi-line);border-radius:19px;overflow:hidden}.pi-safety-list>div{display:grid;grid-template-columns:46px 1fr;gap:15px;padding:18px 20px;border-bottom:1px solid #e2ebf4}.pi-safety-list>div:last-child{border-bottom:0}.pi-safety-icon{width:42px;height:42px;display:grid;place-items:center;border-radius:13px;background:#eef7ff;border:1px solid #d9eaf8;color:#0d73d3;font-size:9px;font-weight:900}.pi-safety-copy>div{display:flex;align-items:center;gap:9px;flex-wrap:wrap}.pi-safety-copy h3{font-size:13px;margin:0;color:#163b70}.pi-safety-copy em{padding:5px 8px;border-radius:999px;text-transform:uppercase;font-size:7px;letter-spacing:.065em;font-style:normal;font-weight:900}.pi-safety-copy em.safe{background:#def5e9;color:#167a52}.pi-safety-copy em.caution{background:#fff0d8;color:#9d621f}.pi-safety-copy em.danger{background:#ffe0e3;color:#b53e4b}.pi-safety-copy em.neutral{background:#e8f2fc;color:#426d99}.pi-safety-copy p{font-size:11px;line-height:1.58;color:#687f9d;margin:7px 0 0}
.pi-tips-card{display:grid;grid-template-columns:.75fr 1.25fr;gap:32px;padding:38px 40px;border-radius:27px;background:linear-gradient(135deg,#062759,#0a4b94 58%,#0e79c8);color:#fff;box-shadow:0 20px 46px rgba(5,49,103,.2)}.pi-tips-card small{font-size:8px;text-transform:uppercase;letter-spacing:.13em;color:#7dccff;font-weight:900}.pi-tips-card h2{font-size:35px;letter-spacing:-.045em;margin:8px 0}.pi-tips-card>div p{font-size:11px;color:#bdd7ee;line-height:1.55}.pi-tips-card ul{display:grid;gap:9px;margin:0;padding:0;list-style:none}.pi-tips-card li{display:grid;grid-template-columns:24px 1fr;gap:9px;align-items:start}.pi-tips-card li i{width:22px;height:22px;display:grid;place-items:center;border-radius:7px;background:rgba(70,196,255,.16);color:#7bd2ff;font-size:9px;font-style:normal;font-weight:900}.pi-tips-card li span{font-size:11px;line-height:1.5;color:#d8e9f8;padding-top:2px}
.pi-fact-grid{display:grid;grid-template-columns:1fr 1fr;border:1px solid var(--pi-line);border-radius:18px;overflow:hidden}.pi-fact-grid>div{min-height:86px;padding:18px 20px;background:#fbfdff;border-bottom:1px solid var(--pi-line)}.pi-fact-grid>div:nth-child(odd){border-right:1px solid var(--pi-line)}.pi-fact-grid>div:nth-last-child(-n+2){border-bottom:0}.pi-fact-grid span,.pi-fact-grid strong{display:block}.pi-fact-grid span{font-size:8px;text-transform:uppercase;letter-spacing:.1em;color:#7c91ac;margin-bottom:8px}.pi-fact-grid strong{font-size:12px;line-height:1.45;color:#153a6e}
.pi-interaction-list{display:grid;gap:0;margin-top:23px;border-top:1px solid var(--pi-line)}.pi-interaction-list>div{display:grid;grid-template-columns:86px 1fr;gap:18px;padding:18px 5px;border-bottom:1px dashed #d8e4f0}.pi-interaction-list>div>span{justify-self:start;padding:6px 9px;border-radius:8px;background:#fff0dd;color:#9e631e;text-transform:uppercase;font-size:7px;letter-spacing:.07em;font-weight:900}.pi-interaction-list h3{font-size:13px;color:#153a70;margin:0 0 5px}.pi-interaction-list p{font-size:11px;line-height:1.55;color:#6b819f;margin:0}
.pi-faq-list{border-top:1px solid var(--pi-line)}.pi-faq-list details{border-bottom:1px solid var(--pi-line)}.pi-faq-list summary{display:flex;align-items:center;justify-content:space-between;gap:20px;padding:19px 2px;cursor:pointer;list-style:none;color:#15396f;font-size:13px;font-weight:800}.pi-faq-list summary::-webkit-details-marker{display:none}.pi-faq-list summary i{width:28px;height:28px;flex:none;display:grid;place-items:center;border-radius:9px;background:#edf6ff;color:#0b75d6;font-size:14px;font-style:normal;transition:.25s}.pi-faq-list details[open] summary i{transform:rotate(45deg);background:#0c72d5;color:#fff}.pi-faq-list details p{padding:0 48px 19px 2px;font-size:12px;line-height:1.68;color:#687f9d;margin:0}
.pi-reference-note{padding:20px 24px;border-radius:20px;background:#edf5fd;border:1px solid #d9e7f4}.pi-reference-note>b{font-size:11px;text-transform:uppercase;letter-spacing:.09em;color:#315c8e}.pi-reference-note p{font-size:10px;line-height:1.55;color:#7186a1;margin:7px 0 12px}.pi-reference-note>div{display:flex;gap:8px;flex-wrap:wrap}.pi-reference-note a{padding:8px 10px;border-radius:9px;background:#fff;border:1px solid #d7e5f2;color:#0c67c2;font-size:9px;font-weight:800}
.pi-sidebar{position:sticky;top:150px;display:grid;gap:17px}.pi-sidebar-card{padding:22px;border-radius:23px;background:#fff;border:1px solid var(--pi-line);box-shadow:0 14px 32px rgba(13,60,112,.065)}.pi-sidebar-product>img{width:100%;aspect-ratio:16/11;object-fit:contain;border-radius:15px;background:#f5faff;margin:7px 0 16px}.pi-sidebar-product h2{font-size:25px;letter-spacing:-.04em;color:#0b326b;margin:0}.pi-sidebar-product>p{font-size:10px;line-height:1.55;color:#687f9d;margin:8px 0 15px}.pi-sidebar-product dl{margin:0}.pi-sidebar-product dl>div{display:flex;justify-content:space-between;gap:15px;padding:9px 0;border-top:1px solid #e4edf6}.pi-sidebar-product dt{font-size:9px;color:#8194ad}.pi-sidebar-product dd{font-size:9px;color:#254d7a;font-weight:800;text-align:right;margin:0}.pi-sidebar-product>a{display:flex;align-items:center;justify-content:space-between;margin-top:15px;padding:13px 14px;border-radius:12px;background:linear-gradient(135deg,#0d5fc9,#138be9);color:#fff;font-size:10px;font-weight:900}
.pi-professional-note{background:linear-gradient(145deg,#082d65,#0b559c);border-color:transparent;color:#fff}.pi-professional-note>span{font-size:8px;text-transform:uppercase;letter-spacing:.12em;color:#7fd0ff;font-weight:900}.pi-professional-note h3{font-size:21px;letter-spacing:-.035em;margin:9px 0}.pi-professional-note p{font-size:10px;line-height:1.62;color:#c5dcf1;margin:0}
.pi-related-card>h3{font-size:18px;color:#12396f;margin:5px 0 15px}.pi-related-card>a:not(.pi-view-all){display:grid;grid-template-columns:48px 1fr auto;gap:10px;align-items:center;padding:10px 0;border-top:1px solid #e4edf6}.pi-related-card>a>img{width:48px;height:39px;object-fit:contain;object-position:center;border-radius:9px;background:#f3f8fd}.pi-related-card a b,.pi-related-card a small{display:block}.pi-related-card a b{font-size:10px;color:#173e72}.pi-related-card a small{font-size:8px;color:#7f92aa;margin-top:3px}.pi-related-card a>span{color:#0b74d4}.pi-view-all{display:flex!important;align-items:center;justify-content:space-between!important;margin-top:12px;padding:11px 12px!important;border-radius:11px!important;background:#eef7ff;color:#0c67c3;font-size:9px;font-weight:900}
.pi-disclaimer{padding:36px 0;background:#061f4c;color:#fff}.pi-disclaimer .container{display:grid;grid-template-columns:190px 1fr auto;gap:28px;align-items:center}.pi-disclaimer span{font-size:9px;text-transform:uppercase;letter-spacing:.12em;color:#73caff;font-weight:900}.pi-disclaimer p{font-size:11px;line-height:1.65;color:#bfd4e8;margin:0}.pi-disclaimer a{padding:11px 14px;border-radius:10px;background:rgba(255,255,255,.09);border:1px solid rgba(255,255,255,.15);color:#fff;font-size:9px;font-weight:850;white-space:nowrap}
@media(max-width:1100px){
  .pi-hero-layout{gap:38px}.pi-hero-visual{min-height:440px}.pi-visual-orbit{width:440px;height:440px}.pi-content-layout{grid-template-columns:minmax(0,1fr) 290px}.pi-section-card{padding:34px}.pi-benefit-grid{grid-template-columns:1fr}.pi-alert-list{grid-template-columns:1fr}
}
@media(max-width:900px){
  .pi-section-nav{top:72px}.pi-hero-layout{grid-template-columns:1fr;padding:38px 0 65px}.pi-hero-copy{max-width:760px}.pi-hero-visual{min-height:500px}.pi-content-layout{grid-template-columns:1fr}.pi-sidebar{position:static;grid-template-columns:1fr 1fr}.pi-sidebar-product{grid-row:span 2}.pi-disclaimer .container{grid-template-columns:1fr}.pi-disclaimer a{justify-self:start}
}
@media(max-width:680px){
  .pi-breadcrumb{padding-top:18px}.pi-breadcrumb a:nth-of-type(2),.pi-breadcrumb a:nth-of-type(2)+span{display:none}.pi-hero-layout{padding:28px 0 49px;gap:28px}.pi-hero h1{font-size:49px}.pi-product-label{font-size:9px}.pi-composition-card{padding:16px}.pi-composition-card strong{font-size:14px}.pi-summary{font-size:14px}.pi-hero-actions{flex-direction:column}.pi-primary-action,.pi-secondary-action{width:100%}.pi-hero-visual{min-height:350px}.pi-visual-orbit{width:330px;height:330px}.pi-product-frame{border-radius:22px;padding:7px}.pi-product-frame>img{border-radius:16px}.pi-rx-note{position:relative;left:auto;bottom:auto;width:100%;max-width:none;margin-top:10px}.pi-contact-strip .container{grid-template-columns:38px 1fr}.pi-contact-icon{width:36px;height:36px}.pi-contact-strip>a{grid-column:1/-1;justify-content:space-between}.pi-section-nav{top:68px}.pi-section-nav a{padding:13px 10px;font-size:8px}.pi-content{padding:38px 0 58px}.pi-main-column{gap:15px}.pi-section-card{padding:25px 20px;border-radius:21px}.pi-section-heading{gap:11px;margin-bottom:21px}.pi-section-heading>span{width:36px;height:36px;border-radius:11px}.pi-section-heading h2{font-size:29px}.pi-context-note,.pi-urgent-note{grid-template-columns:1fr;gap:6px}.pi-benefit-grid,.pi-two-column{grid-template-columns:1fr}.pi-two-column{gap:15px}.pi-alert-list{grid-template-columns:1fr}.pi-safety-list>div{grid-template-columns:38px 1fr;padding:15px 13px}.pi-safety-icon{width:36px;height:36px}.pi-tips-card{grid-template-columns:1fr;padding:27px 22px}.pi-fact-grid{grid-template-columns:1fr}.pi-fact-grid>div,.pi-fact-grid>div:nth-child(odd),.pi-fact-grid>div:nth-last-child(-n+2){border-right:0;border-bottom:1px solid var(--pi-line)}.pi-fact-grid>div:last-child{border-bottom:0}.pi-interaction-list>div{grid-template-columns:1fr;gap:8px}.pi-sidebar{grid-template-columns:1fr}.pi-sidebar-product{grid-row:auto}.pi-disclaimer{padding:28px 0}.pi-disclaimer .container{gap:12px}
}